Following are the most common cancer predisposition syndromes. Each syndrome name links to more detailed information, including causes, diagnosis, cancer risk and screening, and special considerations for children with the syndrome.
Beckwith-Wiedemann Spectrum and Lateralized Overgrowth
Constitutional Mismatch Repair Deficiency Syndrome (CMMRD)
Familial Adenomatous Polyposis
Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome
Hereditary Paraganglioma-Pheochromocytoma Syndrome
Multiple Endocrine Neoplasia Type 1
Multiple Endocrine Neoplasia Type 2
Nevoid Basal Cell Carcinoma Syndrome
Noonan Syndrome and other RASopathies
Rhabdoid Tumor Predisposition Syndrome
Adapted from educational materials developed by the St. Jude Children’s Research Hospital Cancer Predisposition Program